DNBSEQ-T1+

Overview

The DNBSEQ-T1+, powered by DNBSEQ™ technology, streamlines the DNB preparation and loading process with onboard "DNB Make and Load" technology, enabling a one-click, quantification-free workflow for these steps. It is a highly efficient mid-throughput sequencer with Q40 accuracy, delivering 55 Gb to 1.2 Tb of data per run.

Core DNBSEQ™ Sequencing Technology

DNBSEQ™ Technology combines DNA nanoball (DNB) rolling-circle amplification with patterned array loading and combinatorial probe-anchor synthesis (cPAS). Because each DNB is a clonal copy that does not amplify during sequencing, the chemistry avoids the error accumulation, index hopping, and duplication of bridge-amplification platforms, delivering high accuracy with low duplication rates. All MGI sequencers can run as standalone systems from sample to result without any network connection, keeping data fully secure.

Key Highlights

Data output of 55 Gb to 1.2 Tb per run with read lengths from SE50 to PE300.

Onboard "DNB Make and Load" technology enables a one-click, quantification-free DNB preparation and loading workflow.

Q40 sequencing accuracy for high-confidence variant calling.

Simple, rapid, and flexible operation for mid-throughput laboratories.

Applications

Whole-genome sequencing, exome and large panel sequencing, transcriptomic sequencing, methylation sequencing, and metagenomic profiling.

Data Security and Bioinformatics

Every MGI platform can operate as a standalone system from sample to result with no network connection, eliminating the risk of data breaches. On the analysis side, MGI's bioinformatics accelerators speed up secondary analysis: MegaBOLT reduces computational delays by up to 20 times over classical algorithms, and ZBOLT Pro, the ultra-high-performance version, achieves up to a 200 times increase in data analysis speed.

Specifications