DNBSEQ-G99

Overview

The DNBSEQ-G99 is the fastest benchtop NGS sequencer, designed for mid-to-low-throughput applications such as targeted gene and small genome sequencing. Powered by DNBSEQ™ technology, it provides rapid sequencing with a flexible throughput of 2 Gb to 120 Gb per run and completes PE150 sequencing in just 11 hours. Its dual flow cell design, advanced biochemistry and optics, and an integrated bioinformatics module ensure high-quality data output and precision across a wide range of genomic research needs.

Core DNBSEQ™ Sequencing Technology

DNBSEQ™ Technology combines DNA nanoball (DNB) rolling-circle amplification with patterned array loading and combinatorial probe-anchor synthesis (cPAS). Because each DNB is a clonal copy that does not amplify during sequencing, the chemistry avoids the error accumulation, index hopping, and duplication of bridge-amplification platforms, delivering high accuracy with low duplication rates. All MGI sequencers can run as standalone systems from sample to result without any network connection, keeping data fully secure.

Key Highlights

Flexible throughput from 2 Gb to 120 Gb per run with read lengths from SE100 to PE300.

Completes PE150 sequencing in approximately 11 hours — the fastest benchtop turnaround in its class.

Dual flow cell design allows independent runs for maximum scheduling flexibility.

Integrated bioinformatics module provides rapid preliminary reports.

Applications

Targeted gene sequencing, small whole-genome sequencing, targeted gene expression, 16S metagenomic sequencing, and rapid pathogen and microbial studies.

Data Security and Bioinformatics

Every MGI platform can operate as a standalone system from sample to result with no network connection, eliminating the risk of data breaches. On the analysis side, MGI's bioinformatics accelerators speed up secondary analysis: MegaBOLT reduces computational delays by up to 20 times over classical algorithms, and ZBOLT Pro, the ultra-high-performance version, achieves up to a 200 times increase in data analysis speed.

Specifications